Abstract
Peliosanthes micrantha species is traditionally employed in the Dak Nong province of Vietnam for its supposed properties in improving male sexuality. The objective of this study was to evaluate the impact of P. micrantha ethanolic rhizome extract administration on sexual performance in inexperienced male sprague-dawley rats. The following sexual performances were evaluated: body weights, weights of reproductive organs, and levels of testosterone for repeated doses of 7 days; several parameters including mount behaviors such as Mount Frequency (MF), Mount Latency (ML); intromission behaviors such as Intromission Frequency (IF), Intromission Latency (IL), Intromission Efficiency (IE); ejaculation behaviors such as Ejaculation Frequency (EF), Post Ejaculatory Interval (PEI), Ejaculation Latency (EL); and Copulatory Efficiency behavior (CE) for single dose and repeated doses of 7 days. Results from the 7 days repeated-dose experiment showed increases in body weights, up to 9.00%, slight changes in reproductive organs’ weights, and a significant increase in serum testosterone levels in extract-treated rats. The tested extracts showed different effects of sexual behavior parameters between acute single doses and subacute repeated doses during 7 days of P. micrantha rhizomes ethanolic extract administration. Our results indicated that the repeated and high doses have better effects in Mount Latency (ML), and Intromission Frequency (IF). On the contrary, the repeated and low doses have better effects in Intromission Latency (IL).
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