Abstract
Background: Gestational Diabetes Mellitus (GDM) is associated with a high risk of recurrence, particularly in women of advanced maternal age and high parity. Evidence on the prevention of recurrent GDM in the setting of great-grand multiparity remains limited.
Case Presentation: We report the obstetric history and management of a 42-year-old great-grand multiparous woman (para 10) in whom recurrence of GDM was successfully interrupted during her eighth pregnancy. This case details the tailored management strategies adopted in a clinical context characterized by advanced maternal age and extremely high parity, a condition that is rare in Northeast Italy.
Management and Results: Despite the patient’s high-risk profile, this case underscores that recurrence of GDM may be interrupted through targeted preconception and gestational interventions. These include weight reduction, restoration of pre-pregnancy BMI, and adherence to Institute of Medicine 2009 recommended Gestational Weight Gain (GWG) guidelines. This may occur even in high-risk contexts such as advanced maternal age and great-grand multiparity. Multidisciplinary care and individualized counselling remain essential. These approaches support behavioral and metabolic optimization before and during pregnancy.
Conclusions: This case highlights that great-grand multiparity, although uncommon, should not be inherently discouraged. With careful metabolic optimization and personalized lifestyle interventions, recurrence of GDM may be successfully prevented even in highly complex obstetric scenarios. The experience described may provide practical insights for clinicians managing similarly high-risk pregnancies.
Menu