Articles

Uncovered self-expanding metal stent placement for unresectable malignant biliary obstruction: Hope or Hype?

Lalit Chandra K, Venkatesh Vaithiyam, Sanjeev Sachdeva, Ashok Dalal, Ujjwal Sonika, Ajay Kumar, Barjesh Chander S, Siddharth Srivastava

 

Clin Insight Rep J Glob Med Cases 2026, Vol 1(Issue 2), 7.

Abstract: Background: Biliary drainage is recommended for unresectable malignant Extrahepatic Biliary Obstruction (EHBO) to palliate jaundice, pruritus, and cholangitis, yet real-world data from India on uncovered Self-Expanding Metal Stents (SEMS) remain limited. Methods: This single-center retrospective analysis of prospectively collected data from GB Pant Hospital, New Delhi, evaluated stent patency

Expanding the Phenotypic Spectrum of KCNT2-Related Encephalopathy: A Novel de Novo Stop-Gain Variant with Coffin–Siris–Like Features

Hari Prasath C, Anil Kumar P

 

Clin Insight Rep J Glob Med Cases 2026, Vol 1(Issue 2), 6.

Abstract: Pathogenic variants in KCNT2 have recently been recognized as a rare cause of Developmental and Epileptic Encephalopathy (DEE-57), characterized by early-onset refractory seizures and severe neurodevelopmental impairment, with only a limited number of cases reported worldwide. We describe a 7-month-old female infant, born to non-consanguineous parents, who presented with

Delayed Diagnosis of Tuberculous Meningitis in an Elderly Male: A Case Report

Kelly Silnes, Elina Garg, Lomash Sood, Rabinder Randhawa

 

Clin Insight Rep J Glob Med Cases 2026, Vol 1(Issue 1), 5.

Abstract: Background: Tuberculous Meningitis (TBM) remains a significant global health concern, with over 164,000 cases occurring annually worldwide with a mortality rate of approximately 48%. Despite England’s status as a country with low rates of tuberculosis, recent data shows a concerning 11% increase in TB notifications in 2023, with extrapulmonary

In Vivo Efficacy of Ethanol Extract from Peliosanthes Micrantha Rhizomes on Serum Testosterone and Sexual Behavior Parameters in Male Sprague-Dawley Rats

Do Ngoc Thuy, Le Ngoc Hung, Nguyen Thi Huong, Le Minh Ha, Phung Van Trung, Do Thi Nguyet Que, Mai Van Nam

 

Clin Insight Rep J Glob Med Cases 2026, Vol 1(Issue 1), 4.

Abstract: Peliosanthes micrantha species is traditionally employed in the Dak Nong province of Vietnam for its supposed properties in improving male sexuality. The objective of this study was to evaluate the impact of P. micrantha ethanolic rhizome extract administration on sexual performance in inexperienced male sprague-dawley rats. The following sexual

Assessment of Iron Profile and some Hematological Parameters among Regular Blood Donors at the National Blood Transfusion Service (NBTS), Owerri

Iheanacho MC, Amadi UV, Ogunnaya FU, Atiegha C

 

Clin Insight Rep J Glob Med Cases 2026, Vol 1(Issue 1), 3.

Abstract: Regular blood donation is essential for maintaining adequate blood supplies but may predispose donors to iron depletion and anemia if not properly monitored. Repeated blood loss leads to progressive iron deficiency, which can adversely affect hematological parameters and compromise donor health, particularly in settings with limited nutritional support. This

Correction of Erythrocyte Surface Charge by Magnetite Nanoparticles: Bridging Biophysics and Clinical Application

Belousov AN

 

Clin Insight Rep J Glob Med Cases 2026, Vol 1(Issue 1), 2.

Abstract: The reduction of erythrocyte Electrophoretic Mobility (EPM) is an important diagnostic marker of pathological conditions. In in vitro studies, severe toxemia decreased EPM by 64.0% and membrane ζ-potential by 39.5% compared to the control group. Treatment of blood with biocompatible magnetite nanoparticles (brand MCS-B) restored both parameters toward normal

The Challenge of Recurrent Gestational Diabetes in a Great- Grand Multiparity: A Case Report and Literature Review

Vincenzo Zanardo, Lorenzo Severino, Beatrice Zanardo, Francesca Volpe, Rita Maione, Gianluca Straface

 

Clin Insight Rep J Glob Med Cases 2026, Vol 1(Issue 1), 1.

Abstract: Background: Gestational Diabetes Mellitus (GDM) is associated with a high risk of recurrence, particularly in women of advanced maternal age and high parity. Evidence on the prevention of recurrent GDM in the setting of great-grand multiparity remains limited.Case Presentation: We report the obstetric history and management of a 42-year-old